Isothermal Microcalorimetry to Investigate Non Specific Interactions in Biophysical Chemistry
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چکیده
منابع مشابه
Isothermal Microcalorimetry to Investigate Non Specific Interactions in Biophysical Chemistry
Isothermal titration microcalorimetry (ITC) is mostly used to investigate the thermodynamics of "specific" host-guest interactions in biology as well as in supramolecular chemistry. The aim of this review is to demonstrate that ITC can also provide useful information about non-specific interactions, like electrostatic or hydrophobic interactions. More attention will be given in the use of ITC t...
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The main calorimetric principles used in isothermal microcalorimetry are briefly discussed. Different chemical calibration and test reactions are discussed, with a focus on reactions suitable for ambient conditions: reactions initiated by mixing of liquids (including titration microcalorimetry), dissolution of solid compounds and of slightly soluble gases, a photochemical process, and thermal p...
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Techniques of isothermal microcalorimetry have been much improved during the past two decades. In addition to their use in fundamental research, applications of practical importance have been established in some areas. However, no significant use of isothermal microcalorimetry has yet been seen in practical applications of biology, despite many methodological studies reported from that area. Th...
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inTroDuCTion When a problem is encountered in the production or storage of solid dosage forms, invariably the problem is somehow connected to the sorption of water. In the presence of water, the physical properties of solids may be altered causing changes in flow properties, free volume, and compressibility; or there may be an accelerated interconversion between polymorphic forms seriously affe...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2009
ISSN: 1422-0067
DOI: 10.3390/ijms10083283